Thread:Arima no megane/@comment-25787298-20151204184508/@comment-26841482-20151205035214

Firstly, Noroi is a male. That bone structure says it all.

Secondly, Karren is insane because Eto mind fucked her with torture.

Bonus point: It's speculated that Eto tortured Takizawa, too. Seidou, though, is not that much insane. So, I guessed that the insanity depends upon the tortured person's own willpower.