Talk:Big Madam/@comment-191.110.184.242-20151107162028/@comment-10733658-20151107162301

TLDR:

Lengthy discussion, decision in cases of ambiguity or trans* to list both the character's designated birth sex (ie: what would be on their birth certificate) and also list their Gender Identity (known or unknown).

So Big Madam is stated to be designated male at birth, but was living as a woman.